Deciding between Spravato (esketamine) and ketamine infusion therapy can be challenging. Ultimately, the choice will depend on a thorough evaluation by a licensed psychiatrist who understands your unique needs. However, it’s helpful to go into this conversation with some background knowledge of your treatment options.
In this blog, we’ll guide you through the key differences between Spravato and ketamine infusions—from how they work to what you can expect—so you can make an informed decision that aligns with your health goals and lifestyle.
How Do Spravato and Ketamine Infusion Work?
Both Spravato and ketamine infusions work by targeting NMDA receptors in the brain, leading to increased levels of glutamate. This process helps restore neural connections, which can rapidly improve mood, reduce suicidal thoughts, and provide relief for individuals who have not responded to traditional treatments. These treatments have been particularly beneficial for those with treatment-resistant depression, anxiety, and PTSD.
Spravato vs. Ketamine Infusions: Administration, Side Effects, and Maintenance
While both therapies can be effective, they differ in administration, side effects, and long-term maintenance. Having a general understanding of Spravato (esketamine) vs. ketamine infusions can help patients choose the most suitable option based on their needs. Below, we break down the key differences between Spravato and ketamine infusions to provide a clearer picture of what to expect.
1. Administration
- SPRAVATO™ (Esketamine): A nasal spray administered twice a week initially, then weekly or biweekly for maintenance. Patients must remain in the clinic for at least two hours after treatment for monitoring.
- Ketamine Infusion: Administered via IV infusion over 40-60 minutes. Typically, patients start with six sessions over two to three weeks, followed by maintenance treatments as needed.
2. Side Effects
- Spravato and Ketamine Infusions: Both treatments may cause dizziness, dissociation, nausea, sedation, and increased blood pressure. The specific side effects you experience may vary between the two treatments. Side effects usually subside within a few hours, but patients are advised not to drive after treatment.
3. Long-Term Use and Maintenance
- Spravato: Requires a structured schedule of weekly or biweekly treatments for maintenance.
- Ketamine infusions: Booster sessions may be needed, but frequency varies by patient response. The average duration of relief between boosters is 3 to 4 weeks.
Now that you understand the core differences between the two treatment options, let’s explore how to determine which therapy might be the best fit for you.
Which Treatment Is Right for You?
Choosing between Spravato (esketamine) and ketamine infusions is a personal decision that depends on several factors, including your medical history, treatment goals, and lifestyle preferences. Here are some key considerations to help guide your decision and discuss with your initial consultation:
- Medical Considerations: If you have a history of high blood pressure or cardiovascular conditions, your provider may recommend one treatment over another based on your need for monitoring potential side effects. Research suggests that ketamine therapy could potentially increase blood pressure, so it’s essential to share your complete medical history with your provider.
- Effectiveness and Side Effects: While both treatments have shown effectiveness for conditions like depression, PTSD, and anxiety, some patients may respond better to one method. If you experience significant side effects with one, your healthcare provider may recommend switching to the alternative to see if your side effects are reduced or the effectiveness of the treatment is enhanced.
- Cost and Insurance Coverage: Spravato is FDA-approved, which means it is more likely to be covered by insurance. In contrast, ketamine infusion therapy is considered off-label, so it may require an out-of-pocket expense. Before starting ketamine treatment for depressionor another mental health condition, check with your insurance provider and discuss pricing with your healthcare provider to ensure financial feasibility.
- Psychological Support: Ketamine therapy often works best when paired with ongoing psychological support, such as therapy. Consider whether you have access to these mental health services as part of your treatment plan.
A consultation with a healthcare provider experienced in ketamine therapy is essential. By discussing your unique medical background and preferences, you can develop a personalized plan that maximizes the potential benefits of ketamine-based therapy while ensuring safety and effectiveness.
Why Choose WIP for Your Spravato or Ketamine Infusion Treatments?
At WIP, we provide compassionate, expert-led ketamine therapies in a safe and comfortable environment. Here’s why patients trust us:
- Experienced Providers: Our specialists have extensive experience in ketamine-based treatments for depression, anxiety, and PTSD.
- Comprehensive Care: We offer both Spravato and IV ketamine infusions, giving you options tailored to your needs.
- State-of-the-Art Facility: Designed for comfort, safety, and relaxation during treatment.
Ready to explore ketamine therapy?
If you’re ready to take the next step in your mental health journey and explore the potential benefits of Spravato or ketamine infusion therapy, WIP is here to help all residents of the D.C., Maryland, and Virginia areas. Our team of experienced providers is committed to guiding you through your options and developing a personalized treatment plan tailored to your needs. Whether you’re interested in the structured regimen of Spravato or the flexibility of ketamine infusions, we can help you navigate the decision-making process and provide the support you need to find relief.
Don’t wait any longer to reclaim your well-being—contact WIP today to schedule a free consultation.
